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KMID : 1188320150090020181
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Gut and Liver
2015 Volume.9 No. 2 p.181 ~ p.187
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Clinical Outcomes of the Endoscopic Submucosal Dissection of Early Gastric Cancer Are Comparable between Absolute and New Expanded Criteria
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Shin Keun-Young
Jeon Seong-Woo
Cho Kwang-Bum
Park Kyung-Sik
Kim Eun-Soo
Park Chang-Keun
Chung Yun-Jin
Kwon Joong-Goo
Kim Eun-Young
Kim Kyeong-Ok
Jang Byung-Ik
Lee Si-Hyung
Park Jeong-Bae
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Abstract
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Background/Aims:Advances in endoscopic submucosal dissection (ESD) techniques have led to the development of expanded criteria for endoscopic resection of early gastric cancer (EGC). The aim of this study was to evaluate the short- and long-term outcomes for ESD using indication criteria.
Methods:A total of 1,105 patients underwent ESD for EGC at six medical centers. The patients were classified into the following two groups based on the lesion size, presence of ulceration and pathological review: an absolute criteria group (n=517) and an expanded criteria group (n=588).
Results:The curative resection rates (91.1% vs 91.3%, p=0.896) were similar in the absolute criteria group and the expanded criteria group. The en bloc resection rates (93.4% and 92.3%, respectively; p=0.488) and complete resection rates (98.3% and 97.4%, respectively; p=0.357) did not differ between the groups. The cumulative disease-free survival rates and the overall survival rates were similar between the groups (p=0.778 and p=0.654, respectively). Independent factors for the curative resection of EGC included tumor location (upper vs middle and lower, 2.632 [1.128?6.144] vs 3.497 [1.560?7.842], respectively) and en bloc resection rate 12.576 [7.442?21.250].
Conclusions:The expanded criteria for ESD in cases of EGC is comparable with the widely accepted pre-existing criteria
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KEYWORD
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Stomach neoplasms, Endoscopy, gastrointestinal, Criteria
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